Job Description

Position Objective: Provide services as a Biologist in support of the overall functions of the Vaccine Research Center (VRC), Vaccine Production Program (VPP) within the National Institute of Allergy and Infectious Diseases (NIAID).
Duties And Responsibilities
Contribute to the generation of stable cell lines for vaccine and therapeutic protein candidates including monoclonal antibodies, recombinant proteins, and virus-like particles.
Prepare plasmid DNA using standard molecular cloning techniques including PCR, restriction digest, and bacterial culture.
Independently execute each step of the cell line development process:
Transfection
Pool generation
Single cell cloning
Clone expansion in static culture plates and shake flasks
Fed-batch analysis
Clone stability studies
Use automated platforms for clone selection and screening.
Participate in cell line development platform design, optimization, and cycle-time reduction studies including methods for clone selection, expansion, ranking, and characterization.
Perform small-scale process development studies using various culture vessels including tissue culture plates, shake flasks, and small-scale bioreactors.
Generate stable pools and perform transient protein production for supply of reagent-grade material
Independently complete experiments and analyze data with minimal supervision.
Provide laboratory support for medium preparation and ordering of supplies.
Write and review technical reports documenting process development studies and stable cell line generation work.
Work with other team members to generate experimental plans for process development studies.
Write and review standard operating procedures for cell line development processes and instrumentation.
Maintain complete documentation records, including a detailed and up-to-date laboratory notebook, to support regulatory filings.
Coordinate cell line development projects in collaboration with the project lead and Federal Task Leader:
Plan experiments to fit within required timelines
Communicate any issues or delays promptly and help to identify solutions
Maintain cell line development master sheet file with all critical information and data
Regularly communicate progress to project lead and present work to cell line development team.
Participate in project meetings.
Contribute results and studies for publication in peer-reviewed journals.
Maintain broad knowledge of state-of-the-art principles.

Job Tags

Similar Jobs

Hunter & Michaels

Job Title: Data Intelligence Analyst Up to $104K (base + bonus) Job at Hunter & Michaels

JOB DESCRIPTION:CPG Beauty Company is seeking a data-literate analystEXPERIENCE:The ideal candidate has 1-3 years experience in CPG data management, Category management or Business Analytics.EDUCATION:Degree is a mustOTHER:-PERCENT TRAVEL:-

Science 37

Travel Per Diem Mobile Research Nurse Job at Science 37

...Science 37's Nursing Solutions Group brings together expert nurses who share a passion for... ...expertise in Science 37's decentralized model of care delivery, the Mobile Research Nurse will... ...Operating Procedures. *This is a travel role that requires on-site visits to...

Red Bull

Student Marketeer - Long Island University Post Job at Red Bull

...As a RedBull Student Marketeer, you are part of the most dynamic and empowered brand and product ambassador program in the world. Reporting to the local Field Marketing Specialist (FMS), you will learn RedBulls target group and are responsible for driving the brand...

Chincoteague Bay Field Station

Marine Science Summer Camp Counselor- Male Dorms Job at Chincoteague Bay Field Station

...either 3 nights or 5 nights at our on campus dorms. The summer sessions are divided by age with groups consisting of 8-9 year olds, 10-12 year olds, 13-15 year olds or 16-18 year olds. CBFS's Summer Camps are structured as a "Build Your Own Adventure" where campers will...

ETCH Transport Company Inc.

FedEx Delivery Driver Job at ETCH Transport Company Inc.

...required. ETCH Transport Company in Central AR partners with FedEx Ground to deliver packages effectively and efficiently to business... ..., we have an immediate need for multiple energetic Delivery Drivers. Due to operating commercial vehicles on state/federal roadways,...

Biologist Job at GAP Solutions, Inc., Gaithersburg, MD

OGVnbUhpS1dVeW9UU2FoRVE3RW94OHB5